In vitro selection of an RNA aptamer yields an interleukin-6/interleukin-6 receptor interaction inhibitor
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Aptamers are small non-coding RNAs capable of recognizing, with high specificity and affinity, a wide variety of molecules in a manner that resembles antibodies. This class of nucleic acids is the resulting product of applying a well-established screening method known as SELEX. First developed in 1990, the SELEX process has become a powerful tool to select structured oligonucleotides for the re...
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ژورنال
عنوان ژورنال: Bioscience, Biotechnology, and Biochemistry
سال: 2021
ISSN: 1347-6947
DOI: 10.1093/bbb/zbaa124